Article
Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy.
European journal of heart failure - 1 Mar 2006
Westermann Dirk, Knollmann Björn C, Steendijk Paul, Rutschow Susanne, Riad Alexander, Pauschinger Matthias, Potter James D, Schultheiss Heinz-Peter, Tschöpe Carsten
Abstract excerpt
BACKGROUND: The cardiac troponin T I79N mutation, linked to familial hypertrophic cardiomyopathy, carries a high risk of sudden cardiac death even in the absence of significant cardiac hypertrophy. The pathology underlying this mechanism has not yet been identified. AIMS: To study the underlying...
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