Article
Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells.
Molecular reproduction and development - 1 Jan 2006
Hata Kenichiro, Kusumi Maki, Yokomine Takaaki, Li En, Sasaki Hiroyuki
Abstract excerpt
The DNA methyltransferase-like protein Dnmt3L is necessary for the establishment of genomic imprints in oogenesis and for normal spermatogenesis (Bourc'his et al., 2001; Hata et al., 2002). Also, a paternally imprinted gene, H19, loses DNA methylation in Dnmt3L-/- spermatogonia (Bourc'his and Bes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
