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Article

Sensor domain of histidine kinase ComD confers competence pherotype specificity in Streptoccoccus pneumoniae.

FEMS microbiology letters - 15 Nov 2005

Iannelli Francesco, Oggioni Marco R, Pozzi Gianni

Abstract excerpt

Competence for genetic transformation in Streptococcus pneumoniae is regulated by a quorum-sensing mechanism involving the pheromone competence stimulating peptide (CSP) encoded by comC and a two-component signal transduction system, ComD-ComE (TCS12). In the presence of CSP, the transmembrane histidine kinase ComD receptor activates the response regulator ComE. The comC, comD and comE genes are part of an operon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16209911
DOI: 10.1016/j.femsle.2005.09.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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