Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive competence for genetic transformation in Streptococcus pneumoniae caused by mutation of a transmembrane histidine kinase.

Molecular microbiology - 1 Nov 2001

Lacks S A, Greenberg B

Abstract excerpt

Competence for DNA uptake and genetic transformation in Streptococcus pneumoniae is regulated by a quorum-sensing system. A competence-stimulating polypeptide (CSP) is secreted by the bacteria and acts back on the cells via a transmembrane histidine kinase. This enzyme phosphorylates a response regulator that activates synthesis of a SigH-like protein. The new sigma factor enables expression of a set of proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaerobiosis
Share to DNA, Bacterial
Share to Genes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histidine Kinase

Share to Plasmids

Share to Protein Kinases

Share to Streptococcus pneumoniae

Share to Transformation, Bacterial

Source

Identifiers

PMID: 11737645
DOI: 10.1046/j.1365-2958.2001.02697.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive competence for genetic transformation in Streptococcus pneumoniae caused by mutation of a transmembrane histidine kinase.PMID 11737645Read ↗

Interconnection of competence, stress and CiaR regulons in Streptococcus pneumoniae: competence triggers stationary phase autolysis of ciaR mutant cells.Semantic proximity Read ↗

Sensor domain of histidine kinase ComD confers competence pherotype specificity in Streptoccoccus pneumoniae.Semantic proximity Read ↗

Inhibition of competence development in Streptococcus pneumoniae by increased basal-level expression of the ComDE two-component regulatory system.Semantic proximity Read ↗

Choline-binding protein D (CbpD) in Streptococcus pneumoniae is essential for competence-induced cell lysis.Semantic proximity Read ↗

Transformation in Streptococcus pneumoniae: mosaic genes and the regulation of competence.Semantic proximity Read ↗

The com locus controls genetic transformation in Streptococcus pneumoniae.Semantic proximity Read ↗

Identification of the streptococcal competence-pheromone receptor.Semantic proximity Read ↗

Genome-Wide Screens Reveal New Gene Products That Influence Genetic Competence in Streptococcus mutans.Semantic proximity Read ↗

Pneumococcal HtrA protease mediates inhibition of competence by the CiaRH two-component signaling system.Semantic proximity Read ↗

Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges.Semantic proximity Read ↗

Dynamic Modeling of Streptococcus pneumoniae Competence Provides Regulatory Mechanistic Insights Into Its Tight Temporal RegulationSemantic proximity Read ↗

Construction and analysis of a library for random insertional mutagenesis in Streptococcus pneumoniae: use for recovery of mutants defective in genetic transformation and for identification of essential genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.