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Article

Use of time-saving flow cytometry for rapid determination of resistance of human cytomegalovirus to ganciclovir.

Journal of clinical microbiology - 1 Oct 2005

Lee Gyu-Cheol, Lee Dong-Gun, Choi Su-Mi, Yoo Jin-Hong, Park Sun-Hee, Choi Jung-Hyun, Min Woo-Sung, Cho Ok-Hee, Lee Chan-Hee, Shin Wan-Shik

Abstract excerpt

There are two ways to assess the susceptibility of human cytomegalovirus (HCMV) to ganciclovir (GCV): one is a genotypic test that detects resistance-related mutations and the other is a phenotypic test that actually assesses susceptibility. The advantages of genotyping the UL 97 gene are its rapidity and accuracy. However, to detect novel mutations or mutations affecting the UL 54 DNA polymerase, a phenotypic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16207954
DOI: 10.1128/JCM.43.10.5003-5008.2005
PMCID: PMC1248522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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