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Article

Astrocyte differentiation selectively upregulates CCL2/monocyte chemoattractant protein-1 in cultured human brain-derived progenitor cells.

Glia - 1 Jan 2006

Lawrence Diane M P, Seth Pankaj, Durham Linda, Diaz Frank, Boursiquot Roosevelt, Ransohoff Richard M, Major Eugene O

Abstract excerpt

Chemokines (chemoattractant cytokines) and their receptors are present in the brain and may play roles in both neurodevelopment and neuropathology. Increased brain levels of monocyte chemoattractant protein-1 (MCP-1), also known as CCL2, are found in patients with human immunodeficiency virus type 1 (HIV-1)-associated dementia and other acute and chronic neurologic diseases. Although the function of CCL2 in the...

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Source

Identifiers

PMID: 16206198
DOI: 10.1002/glia.20261

Genes

CCL2
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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