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Induction of chemokines in human astrocytes by picornavirus infection requires activation of both AP‐1 and NF‐κB

11 Dec 2003

Abstract excerpt

Infection with different picornaviruses can cause meningitis/encephalitis in humans and experimental animals. To investigate the mechanisms of such inflammatory diseases, potential chemokine gene activation in human astrocytes was investigated following infection with Theiler's murine encephalomyelitis virus (TMEV), coxsackievirus B3 (CVB3), or coxsackievirus B4 (CVB4). We report that all these viruses are potent...

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PMID: 14730702
DOI: 10.1002/glia.10331

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