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Article

O-2A glial progenitors from mature brain respond to CNS neuronal cell line-derived growth factors.

Journal of neuroscience research - 1 Apr 1991

Hunter S F, Bottenstein J E

Abstract excerpt

During development, myelin-forming oligodendrocytes and type 2 astrocytes are believed to arise from bipotential (O-2A) glial progenitors. Previously we found that conditioned medium (CM) from the B104 rat CNS neuronal cell line promotes growth of neonatal rat O-2A progenitors in serum-free culture conditions with subsequent increases in differentiated progeny. We now report that O-2A progenitors are present in...

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PMID: 1870158
DOI: 10.1002/jnr.490280415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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