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Lineage pathway of human brain progenitor cells identified by JC virus susceptability

28 Mar 2003

Abstract excerpt

Multipotential human central nervous system progenitor cells, isolated from human fetal brain tissue by selective growth conditions, were cultured as undifferentiated, attached cell layers. Selective differentiation yielded highly purified populations of neurons or astrocytes. This report describes the novel use of this cell culture model to study cell type-specific recognition of a human neurotropic virus, JC...

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PMID: 12730998
DOI: 10.1002/ana.10523

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