Article
HIV-1 gene expression and replication in neuronal and glial cell lines with immature phenotype: effects of nerve growth factor.
Virology - 1 May 1994
Ensoli F, Ensoli B, Thiele C J
Abstract excerpt
Encephalopathy and neurological disorders are a major manifestation of pediatric AIDS. Although HIV-1 can replicate in cells of neuronal and glial origin, it is yet unclear whether immature neural cells, which are present during nervous system development, can support HIV-1 replication and whethe...
Topics
- Cell Differentiation
- Cell Line
- Gene Expression
- Gene Products, tat
- Genes, Reporter
- HIV Long Terminal Repeat
- HIV-1
- Humans
- Nerve Growth Factors
- Neuroglia
- Neurons
- Phenotype
- Stem Cells
- Transcriptional Activation
- Virus Replication
- tat Gene Products, Human Immunodeficiency Virus