Article
HIV-1 gene expression and replication in neuronal and glial cell lines with immature phenotype: effects of nerve growth factor.
Virology - 1 May 1994
Ensoli F, Ensoli B, Thiele C J
Abstract excerpt
Encephalopathy and neurological disorders are a major manifestation of pediatric AIDS. Although HIV-1 can replicate in cells of neuronal and glial origin, it is yet unclear whether immature neural cells, which are present during nervous system development, can support HIV-1 replication and whether neurotrophic factors can modulate HIV-1 gene expression. In this study we show that a glial cell line with a...
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