Article
Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma.
Molecular vision - 23 Sept 2005
Mukhopadhyay Arijit, Komatireddy Sreelatha, Acharya Moulinath, Bhattacharjee Ashima, Mandal Anil Kumar, Thakur Sanjay K D, Chandrasekhar Garudadri, Banerjee Arun, Thomas Ravi, Chakrabarti Subhabrata, Ray Kunal
Abstract excerpt
PURPOSE: To evaluate the role of the optineurin gene (OPTN) in Indian primary open angle glaucoma (POAG) patients from different parts of the country. METHODS: Two hundred patients with POAG and 200 ethnically matched normal controls were recruited from various parts of India for the study. The entire coding region of OPTN along with the intron-exon boundaries were screened by PCR and single strand conformation...
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