Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family.

Molecular vision - 20 Aug 2009

Xiao Zheng, Meng Qingfeng, Tsai James C, Yuan Huiping, Xu Na, Li Yuanyuan

Abstract excerpt

PURPOSE: To identify the genetic mutation associated with distinct cases of open-angle glaucoma noted in a Chinese family. METHODS: Clinical examination and pedigree analysis were undertaken in a family with a large number of primary open-angle glaucoma cases. Venous blood samples were drawn from six affected and six unaffected subjects in the family. Genomic DNA was extracted. Linkage to the optineurin gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Demography
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family

Share to Genetic Linkage

Share to Glaucoma, Open-Angle

Share to Membrane Transport Proteins

Share to Transcription Factor TFIIIA

Source

Open in PubMed Open full text

Identifiers

PMID: 19710941
PMCID: PMC2730747

Genes

OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family.PMID 19710941Read ↗

[Study of novel mutation of OPTN gene in two primary open angle glaucoma families in northeast China].Semantic proximity Read ↗

Different optineurin mutation pattern in primary open-angle glaucoma.Semantic proximity Read ↗

Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population.Semantic proximity Read ↗

Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma.Semantic proximity Read ↗

Mutations in the optineurin gene in Japanese patients with primary open-angle glaucoma and normal tension glaucoma.Semantic proximity Read ↗

Absence of optineurin (OPTN) gene mutations in Taiwanese patients with juvenile-onset open-angle glaucoma.Semantic proximity Read ↗

Four novel optineurin mutations in patients with sporadic amyotrophic lateral sclerosis in Mainland China.Semantic proximity Read ↗

Optineurin coding variants in Ghanaian patients with primary open-angle glaucoma.Semantic proximity Read ↗

Adult-onset primary open-angle glaucoma caused by mutations in optineurin.Semantic proximity Read ↗

Optineurin Gene Polymorpshism and Its Association With Glaucoma OnsetSemantic proximity Read ↗

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read ↗

Analysis of rare variants and common haplotypes in the optineurin gene in Swedish glaucoma cases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.