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Article

Optineurin in primary open angle glaucoma.

Ophthalmology clinics of North America - 1 Dec 2003

Sarfarazi Mansoor, Rezaie Tayebeh

Abstract excerpt

The authors' initial estimate indicated that mutations in Optineurin are responsible for a significant proportion of LPG/POAG families. Currently, there are up to 1.2 million persons with LPG and up to 2.47 million persons with POAG in the United States alone. Perhaps twice as many individuals ar...

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Source

Identifiers

PMID: 14740994
DOI: 10.1016/s0896-1549(03)00061-0

Genes

OPTN
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14740994-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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Optineurin in primary open angle glaucoma.PMID 14740994Read ↗

Adult-onset primary open-angle glaucoma caused by mutations in optineurin.Semantic proximity Read ↗

Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment.Semantic proximity Read ↗

Functional analysis of optineurin and some of its disease-associated mutants.Semantic proximity Read ↗

Optineurin and Its Mutants: Molecules Associated with Some Forms of GlaucomaSemantic proximity Read ↗

Major review: Molecular genetics of primary open-angle glaucoma.Semantic proximity Read ↗

Complex genetics of complex traits: the case of primary open-angle glaucoma.Semantic proximity Read ↗

Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma.Semantic proximity Read ↗

Toward an integrative view of Optineurin functionsSemantic proximity Read ↗

Molecular complexity of primary open angle glaucoma: current concepts.Semantic proximity Read ↗

Posttranslational Modifications, Localization, and Protein Interactions of Optineurin, the Product of a Glaucoma GeneSemantic proximity Read ↗

Meta-analysis of association between optineurin gene and primary open-angle glaucoma.Semantic proximity Read ↗

Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure.Semantic proximity Read ↗

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