Article
Optineurin gene is not involved in the common high-tension form of primary open-angle glaucoma.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Sept 2006
Ariani Francesca, Longo Ilaria, Frezzotti Paolo, Pescucci Chiara, Mari Francesca, Caporossi Aldo, Frezzotti Renato, Renieri Alessandra
Abstract excerpt
PURPOSE: To assess the influence of optineurin in the more common high-tension, primary open-angle glaucoma (POAG). METHODS: Eighteen sporadic cases and 35 probands from 35 familial cases, including three families with one member having normal-tension glaucoma (NTG), were enrolled. Using transgenomic WAVE denaturing high-performance liquid chromatography (DHPLC), all coding portion of the optineurin gene (from...
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