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Article

Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population.

Journal of glaucoma - 1 Aug 2004

Fuse Nobuo, Takahashi Kana, Akiyama Hiroshi, Nakazawa Toru, Seimiya Motohiko, Kuwahara Soichiro, Tamai Makoto

Abstract excerpt

PURPOSE: To determine whether mutations in the optineurin (OPTN) gene are associated with the incidence of primary open-angle glaucoma (POAG) and normal tension glaucoma (NTG) in the Japanese. METHODS: Eighty-nine unrelated Japanese patients with POAG and 65 unrelated patients with NTG were studied. Genomic DNA was extracted from leukocytes of the peripheral blood, and thirteen exons of the OPTN gene were...

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Source

Identifiers

PMID: 15226658
DOI: 10.1097/00061198-200408000-00007

Genes

OPTN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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