Article
The seizure-related phenotype of brain-derived neurotrophic factor knockdown mice.
Neuroscience - 1 Jan 2005
Barton M E, Shannon H E
Abstract excerpt
The present investigation focused on the seizure-related phenotype of mice lacking one allele of brain-derived neurotrophic factor. Thresholds for producing seizures in brain-derived neurotrophic factor wild-type and brain-derived neurotrophic factor heterozygous mice were compared in several seizure models, including thresholds for electrically-induced clonic, tonic-clonic and 6 Hz limbic seizures, as well as...
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