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Article

Polymorphisms in the BER and NER pathways and their influence on survival and toxicity in never-smokers with lung cancer.

Scientific reports - 3 Dec 2020

Casal-Mouriño Ana, Ruano-Ravina Alberto, Torres-Durán María, Parente-Lamelas Isaura, Provencio-Pulla Mariano, Castro-Añón Olalla, Vidal-García Iria, Abal-Arca José, Piñeiro-Lamas María, Fernández-Villar Alberto, Valdés-Cuadrado Luis, Barros-Dios Juan Miguel, Pérez-Ríos Mónica

Abstract excerpt

Polymorphisms in DNA repair pathways may play a relevant role in lung cancer survival in never-smokers. Furthermore, they could be implicated in the response to chemotherapy and toxicity of platinum agents. The aim of this study was to evaluate the influence of various genetic polymorphisms in the BER and NER DNA repair pathways on survival and toxicity in never-smoker LC patients. The study included...

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Identifiers

PMID: 33273562
DOI: 10.1038/s41598-020-78051-5
PMCID: PMC7713126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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