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Article

Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer.

Carcinogenesis - 1 Dec 2004

Popanda Odilia, Schattenberg Torsten, Phong Chi Tai, Butkiewicz Dorota, Risch Angela, Edler Lutz, Kayser Klaus, Dienemann Hendrik, Schulz Volker, Drings Peter, Bartsch Helmut, Schmezer Peter

Abstract excerpt

Several polymorphisms in DNA repair genes have been reported to be associated with lung cancer risk including XPA (-4G/A), XPD (Lys751Gln and Asp312Asn), XRCC1 (Arg399Gln), APE1 (Asp148Glu) and XRCC3 (Thr241Met). As there is little information on the combined effects of these variants, polymorphisms were analyzed in a case-control study including 463 lung cancer cases [among them 204 adenocarcinoma and 212...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15333465
DOI: 10.1093/carcin/bgh264

Genes

XPA
XRCC3
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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