Article
Apolipoprotein E gene polymorphisms in Lebanese with hypercholesterolemia.
Gene - 10 Jun 2013
Mahfouz Rami A, Charafeddine Khalil M, Tanios Rita F, Karaky Nathalie M, Abdul Khalik Rabab N, Daher Rose T
Abstract excerpt
Apolipoprotein E (ApoE) has an important role in the metabolism of lipids through its major isoforms (ε2, ε3, ε4). In particular, ApoE ε4, has been considered as a major genetic risk factor for cardiovascular diseases (CVD). The aim of our study is to investigate the frequency of ApoE gene polymorphisms (rs 429358C>T, rs 7412C>T) and their relationship to lipid parameters in a group of Lebanese...
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