Article
The polymorphism -863C/A in tumour necrosis factor-alpha gene contributes an independent association to gout.
Rheumatology (Oxford, England) - 1 Nov 2007
Chang S-J, Tsai P-C, Chen C-J, Lai H-M, Ko Y-C
Abstract excerpt
OBJECTIVE: To investigate the associations between polymorphisms in the promoter of the tumour necrosis factor-alpha (TNF-alpha) gene and gout. METHODS: The polymorphisms -308G/A and -863C/A in the TNF-alpha gene were determined in 106 gout patients and 159 healthy controls among male Taiwanese using the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) method. The biochemical markers,...
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