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Article

Association analysis of malic enzyme 2 gene polymorphisms with idiopathic generalized epilepsy.

Epilepsia - 1 Oct 2005

Lenzen Kirsten P, Heils Armin, Lorenz Susanne, Hempelmann Anne, Sander Thomas

Abstract excerpt

PURPOSE: Linkage disequilibrium mapping revealed allelic and haplotypic associations between single-nucleotide polymorphisms (SNPs) of the gene encoding the malic enzyme 2 (ME2) and adolescent-onset idiopathic generalized epilepsy (IGE). Homozygote carriers of the associated ME2 haplotype had a sixfold higher risk of IGE compared with any other genotype. The present population-based association study tested...

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Identifiers

PMID: 16190936
DOI: 10.1111/j.1528-1167.2005.00270.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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