Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor alpha 1 and gamma 2 subunit gene cluster on chromosome 5.

Epilepsy research - 1 Apr 1996

Sander T, Hildmann T, Janz D, Wienker T F, Bianchi A, Bauer G, Sailer U, Scaramelli A, Neitzel H, Schmitz B, Bailey M E, Beck-Mannagetta G, Johnson K J, Darlison M G

Abstract excerpt

Hereditary factors play a major role in the etiology of idiopathic generalized epilepsies (IGEs). The pivotal function of ionotropic gamma-aminobutyric acid type A receptors (GABRs) in inhibitory neurotransmission in the mammalian central nervous system suggests that they may be involved in epileptogenesis and genetic predisposition to IGEs. Dinucleotide repeat polymorphisms associated with the human GABAA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Family

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Molecular Sequence Data

Share to Multigene Family

Share to Pedigree

Share to Phenotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8739126
DOI: 10.1016/0920-1211(95)00098-4

Genes

GABRA1
GABRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor alpha 1 and gamma 2 subunit gene cluster on chromosome 5.PMID 8739126Read ↗

Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy.Semantic proximity Read ↗

Lack of evidence of an allelic association of a functional GABRB3 exon 1a promoter polymorphism with idiopathic generalized epilepsy.Semantic proximity Read ↗

Genetics of idiopathic generalized epilepsies.Semantic proximity Read ↗

No evidence for a susceptibility locus for idiopathic generalized epilepsy on chromosome 5 in families with typical absence seizures.Semantic proximity Read ↗

Exploration of the genetic architecture of idiopathic generalized epilepsies.Semantic proximity Read ↗

Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families.Semantic proximity Read ↗

Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modifying genes influencing the seizure type.Semantic proximity Read ↗

Association of rs211037 GABRG2 gene polymorphism with susceptibility to idiopathic generalized epilepsy.Semantic proximity Read ↗

The clinical spectrum of familial and sporadic idiopathic generalized epilepsy.Semantic proximity Read ↗

Do idiopathic generalized epilepsies share a common susceptibility gene?Semantic proximity Read ↗

Association analysis of the Arg220His variation of the human gene encoding the GABA delta subunit with idiopathic generalized epilepsy.Semantic proximity Read ↗

Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.