Article
No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy.
Neuroscience letters - 1 Jan 2000
Lohoff Falk W, Ferraro Thomas N, Sander Thomas, Zhao Hongyu, Dahl John P, Berrettini Wade H, Buono Russell J
Abstract excerpt
Quantitative trait loci studies in inbred mice have identified a locus on chromosome 1 (Szs1) of fundamental importance to seizure susceptibility. High-ranking candidate genes in this susceptibility region include KCNJ9, KCNJ10 and ATP1A2. We performed a systematic mutation scan of the coding region of the human ATP1A2 gene and performed a case-control association study with seven common markers. Genotypes were...
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