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Article

Malic enzyme 2 may underlie susceptibility to adolescent-onset idiopathic generalized epilepsy.

American journal of human genetics - 1 Jan 2005

Greenberg David A, Cayanis Eftihia, Strug Lisa, Marathe Sudhir, Durner Martina, Pal Deb K, Alvin Gabriele B, Klotz Irene, Dicker Elisa, Shinnar Shlomo, Bromfield Edward B, Resor Stanley, Cohen Jeffrey, Moshe Solomon L, Harden Cynthia, Kang Harriet

Abstract excerpt

Idiopathic generalized epilepsy (IGE) is a class of genetically determined, phenotypically related epilepsy syndromes. Linkage analysis identified a chromosome 18 locus predisposing to a number of adolescent-onset IGEs. We report a single-nucleotide polymorphism (SNP) association analysis of the region around the marker locus with the high LOD score. This analysis, which used both case-control and family-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 18

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Share to Genes, Recessive

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Source

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Identifiers

PMID: 15532013
DOI: 10.1086/426735
PMCID: PMC1196416

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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