Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.

Molecular and cellular probes - 1 Aug 2000

Haug K, Kremerskothen J, Hallmann K, Sander T, Dullinger J, Rau B, Beyenburg S, Lentze M J, Barnekow A, Elger C E, Propping P, Heils A

Abstract excerpt

Idiopathic generalized epilepsy (IGE) comprises a heterogeneous group of disorders, in which a high genetic predisposition and a complex mode of inheritance have been suggested. However, genes, which confer liability to common IGE subtypes including juvenile myoclonic epilepsy (JME) and childhood absence epilepsy (CAE) have not been identified so far. Here, we tested the hypothesis that genetic variation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Chromosomes, Human, Pair 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

Share to Epilepsy, Generalized

Share to Genes, Immediate-Early

Share to Nerve Tissue Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Analysis

Source

Identifiers

PMID: 10970730
DOI: 10.1006/mcpr.2000.0314

Genes

ARC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.PMID 10970730Read ↗

Genome search for susceptibility loci of common idiopathic generalised epilepsies.Semantic proximity Read ↗

Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modifying genes influencing the seizure type.Semantic proximity Read ↗

Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy.Semantic proximity Read ↗

Possible association of a silent polymorphism in the neuronal nicotinic acetylcholine receptor subunit alpha4 with common idiopathic generalized epilepsies.Semantic proximity Read ↗

Association of the 867Asp variant of the human anion exchanger 3 gene with common subtypes of idiopathic generalized epilepsy.Semantic proximity Read ↗

Exploration of the genetic architecture of idiopathic generalized epilepsies.Semantic proximity Read ↗

Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis.Semantic proximity Read ↗

No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy.Semantic proximity Read ↗

Mapping of genes predisposing to idiopathic generalized epilepsySemantic proximity Read ↗

Mutational analysis of CACNA1G in idiopathic generalized epilepsy. Mutation in brief #962. Online.Semantic proximity Read ↗

Failure to replicate an allelic association between an exon 8 polymorphism of the human alpha(1A) calcium channel gene and common syndromes of idiopathic generalized epilepsy.Semantic proximity Read ↗

The gene encoding the alpha1A-voltage-dependent calcium channel (CACN1A4) is not a candidate for causing common subtypes of idiopathic generalized epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.