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Article

Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis.

Epilepsy research - 1 May 2010

Muhle Hiltrud, von Spiczak Sarah, Gaus Verena, Kara Serife, Helbig Ingo, Hampe Jochen, Franke Andre, Weber Yvonne, Lerche Holger, Kleefuss-Lie Ailing A, Elger Christian E, Schreiber Stefan, Stephani Ulrich, Sander Thomas

Abstract excerpt

BACKGROUND: GRM4 encoding the group III metabotropic glutamate receptor 4 (mGluR4), is located on the chromosomal segment 6p21.3 where tentative susceptibility loci for Juvenile Myoclonic Epilepsy (JME) and Photoparoxysmal Response (PPR) have been mapped. The present candidate gene study examined if variation in GRM4 confers susceptibility to IGE. PATIENTS AND METHODS: The case-control association sample included...

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Source

Identifiers

PMID: 20338729
DOI: 10.1016/j.eplepsyres.2010.02.004

Genes

GRM4

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