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Article

Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury.

Journal of neurochemistry - 1 Oct 2005

Bacich Dean J, Wozniak Krystyna M, Lu X-C May, O'Keefe Denize S, Callizot Noelle, Heston Warren D W, Slusher Barbara S

Abstract excerpt

Excessive glutamate release is associated with neuronal damage. A new strategy for the treatment of neuronal injury involves inhibition of the neuropeptidase glutamate carboxypeptidase II (GCP II), also known as N-acetylated alpha-linked acidic dipeptidase. GCP II is believed to mediate the hydro...

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Source

Identifiers

PMID: 16190866
DOI: 10.1111/j.1471-4159.2005.03361.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16190866-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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