Article
Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis isolates collected in Australia.
Antimicrobial agents and chemotherapy - 1 Oct 2005
Lavender Caroline, Globan Maria, Sievers Aina, Billman-Jacobe Helen, Fyfe Janet
Abstract excerpt
Elucidation of the molecular basis of isoniazid (INH) resistance in Mycobacterium tuberculosis has led to the development of different genotypic approaches for the rapid detection of INH resistance in clinical isolates. Mutations in katG, in particular the S315T substitution, are responsible for...
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