Article
Elevated levels of mannose-binding lectin at clinical manifestation of type 1 diabetes in juveniles.
Diabetes - 1 Oct 2005
Bouwman Lee H, Eerligh Peter, Terpstra Onno T, Daha Mohamed R, de Knijff Peter, Ballieux Bart E P B, Bruining G Jan, van der Slik Arno R, Roos Anja, Roep Bart O
Abstract excerpt
Mannose-binding lectin (MBL) is a recognition molecule of the lectin pathway of complement and a key component of innate immunity. MBL polymorphisms have been described that are associated with MBL serum concentration, impaired function, and diabetic complications. We investigated 86 new-onset juvenile type 1 diabetic patients and compared these with their nondiabetic siblings and healthy unrelated control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.