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Panning for gold: genome-wide scanning for linkage in type 1 diabetes

1 Sept 1996

Abstract excerpt

Genome-wide scans for linkage of chromosome regions to type 1 diabetes in affected sib pair families have revealed that the major susceptibility locus resides within the major histocompatibility complex (MHC) on chromosome 6p21 (lambda S = 2.4). It is recognized that the MHC contains multiple susceptibility loci (referred to collectively as IDDM1), including the class II antigen receptor genes, which control the...

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PMID: 8875250
DOI: 10.1093/hmg/5.supplement_1.1443

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