Article
Intra-host evolutionary dynamics of hepatitis C virus E2 in treated patients.
The Journal of general virology - 1 Oct 2005
Alfonso Victoria, Mbayed Viviana Andrea, Sookoian Silvia, Campos Rodolfo Héctor
Abstract excerpt
Hepatitis C virus (HCV) displays high genetic diversity. Inter-host sequence variability may mainly reflect a neutral drift evolution. In contrast, intra-host evolution may be driven by an adaptive selection to host responses to infection. Here, HCV E2 intra-host evolution in two patients during...
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