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Article

The mode and tempo of hepatitis C virus evolution within and among hosts

19 May 2011

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) is a rapidly-evolving RNA virus that establishes chronic infections in humans. Despite the virus' public health importance and a wealth of sequence data, basic aspects of HCV molecular evolution remain poorly understood. Here we investigate three sets of whole HCV genomes in order to directly compare the evolution of whole HCV genomes at different biological levels: within- and...

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PMID: 21595904
DOI: 10.1186/1471-2148-11-131

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