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Article

Rapid genotyping of lipopolysaccharide-binding protein (LBP) C(1341)-->T (Leu(436)-->Phe) polymorphism by LightCycler real-time PCR.

Journal of immunological methods - 20 Dec 2006

Korhonen Taina, Grauling-Halama Silke, Halama Niels, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka

Abstract excerpt

Lipopolysaccharide (LPS) is an exdotoxin found in the outer membrane of gram-negative bacteria. In circulation, LPS is bound by LPS-binding protein (LBP), which participates in cell activation by transferring LPS to CD14 and Toll-like receptor 4. A high LPS concentration may give rise to an exaggerated immune response, which may lead to septic shock during septicemia. However, LBP also neutralizes and removes LPS...

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Identifiers

PMID: 17101145
DOI: 10.1016/j.jim.2006.07.029

Genes

LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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