Article
Rapid genotyping of lipopolysaccharide-binding protein (LBP) C(1341)-->T (Leu(436)-->Phe) polymorphism by LightCycler real-time PCR.
Journal of immunological methods - 20 Dec 2006
Korhonen Taina, Grauling-Halama Silke, Halama Niels, Silvennoinen-Kassinen Sylvi, Leinonen Maija, Saikku Pekka
Abstract excerpt
Lipopolysaccharide (LPS) is an exdotoxin found in the outer membrane of gram-negative bacteria. In circulation, LPS is bound by LPS-binding protein (LBP), which participates in cell activation by transferring LPS to CD14 and Toll-like receptor 4. A high LPS concentration may give rise to an exagg...
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