Article
Mannose-binding lectin 2 (MBL2) gene polymorphism in asthma and atopy among adults.
Clinical and experimental immunology - 1 Oct 2005
Aittoniemi J, Soranummi H, Rovio A T, Hurme M, Pessi T, Nieminen M, Karjalainen J
Abstract excerpt
Mannose-binding lectin (MBL) insufficiency due to polymorphisms in the MBL2 gene causes an opsonization defect, which has been connected to infections and atopy. We investigated the significance of MBL2 genotypes with regard to persistent asthma and atopy among adults. The genotypes were determined in 243 adults with persistent asthma and 400 controls. Atopy was determined by skin-prick test. As a result, the...
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