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Article

Legionella pneumophila NudA Is a Nudix hydrolase and virulence factor.

Infection and immunity - 1 Oct 2005

Edelstein Paul H, Hu Baofeng, Shinzato Takashi, Edelstein Martha A C, Xu Wenlian, Bessman Maurice J

Abstract excerpt

We studied the identity and function of the 528-bp gene immediately upstream of Legionella pneumophila F2310 ptsP (enzyme I(Ntr)). This gene, nudA, encoded for a Nudix hydrolase based on the inferred protein sequence. NudA had hydrolytic activity typical of other Nudix hydrolases, such as Escherichia coli YgdP, in that Ap(n)A's, in particular diadenosine pentaphosphate (Ap(5)A), were the preferred substrates....

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Identifiers

PMID: 16177332
DOI: 10.1128/IAI.73.10.6567-6576.2005
PMCID: PMC1230914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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