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Article

microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1.

PloS one - 1 Jan 2017

Jentho Elisa, Bodden Malena, Schulz Christine, Jung Anna-Lena, Seidel Kerstin, Schmeck Bernd, Bertrams Wilhelm

Abstract excerpt

BACKGROUND: Legionella pneumophila (L. pneumophila) is a causative agent of severe pneumonia. It is highly adapted to intracellular replication and manipulates host cell functions like vesicle trafficking and mRNA translation to its own advantage. However, it is still unknown to what extent microRNAs (miRNAs) are involved in the Legionella-host cell interaction. METHODS: WT and MyD88-/- murine bone marrow-derived...

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Identifiers

PMID: 28445535
DOI: 10.1371/journal.pone.0176204
PMCID: PMC5406027

Genes

NTAN1

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