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Article

Study of the genetic stability of measles virus CAM-70 vaccine strain after serial passages in chicken embryo fibroblasts primary cultures.

Virus genes - 1 Feb 2008

Borges Maria Beatriz, Caride Elena, Jabor Alfredo V, Malachias José Marcus N, Freire Marcos S, Homma Akira, Galler Ricardo

Abstract excerpt

To evaluate the genetic stability of the CAM-70 measles vaccine strain we have performed 10 serial passages of the seed lot virus FMS-7 in chicken embryo fibroblasts primary cultures (CEF) under production conditions. The nucleotide sequences of the seed lot virus, the virus from a vaccine vial (third passage) and from the 10th passage were determined and compared with each other and with sequences from other...

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Identifiers

PMID: 18040767
DOI: 10.1007/s11262-007-0173-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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