Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adults

20 Sept 2005

Abstract excerpt

The protein kinase gene family is the most frequently mutated in human cancer. Previous work has documented activating mutations in the KIT receptor tyrosine kinase in testicular germ-cell tumors (TGCT). To investigate further the potential role of mutated protein kinases in the development of TGCT and to characterize the prevalence and patterns of point mutations in these tumors, we have sequenced the coding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Multiple Myeloma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Testicular diseases and treatments

Source

Identifiers

PMID: 16175573
DOI: 10.1002/gcc.20265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence analysis of the protein kinase gene family in human testicular germ‐cell tumors of adolescents and adultsPMID 16175573Read ↗

Somatic mutations in human cancer: insights from resequencing the protein kinase gene family.Semantic proximity Read ↗

Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas.Semantic proximity Read ↗

Genomic characteristics revealed by targeted exon sequencing of testicular germ cell tumors in Japanese men.Semantic proximity Read ↗

KIT mutations are common in testicular seminomas.Semantic proximity Read ↗

Somatic mutation detection and KRAS amplification in testicular germ cell tumorsSemantic proximity Read ↗

Germline-Activating Mutation in the Kinase Domain of KIT Gene in Familial Gastrointestinal Stromal TumorsSemantic proximity Read ↗

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.Semantic proximity Read ↗

Amplification and Overexpression of the <i>KIT</i> Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and AdultsSemantic proximity Read ↗

Somatic mutations of the protein kinase gene family in human lung cancer.Semantic proximity Read ↗

Activating c-kit Gene Mutations in Human Germ Cell TumorsSemantic proximity Read ↗

KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literatureSemantic proximity Read ↗

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.