Article
Heterodimerization of ecdysone receptor and ultraspiracle on symmetric and asymmetric response elements.
Archives of insect biochemistry and physiology - 1 Oct 2005
Perera Srini C, Zheng Sichun, Feng Qi-Li, Krell Peter J, Retnakaran Arthur, Palli Subba R
Abstract excerpt
Heterodimerization of nuclear receptors is facilitated by the interaction of two dimerization interfaces: one spanning the DNA-binding (C domain) region and the adjacent hinge (D domain) region, and the other in the ligand-binding (E domain) region. Ultraspiracle (USP) heterodimerizes with ecdysone receptor (EcR) and this complex participates in ecdysone signal transduction. The natural ecdysone response elements...
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