Article
Systemic lupus erythematosus and the extended major histocompatibility complex--evidence for several predisposing loci.
Rheumatology (Oxford, England) - 1 Nov 2005
Smerdel-Ramoya A, Finholt C, Lilleby V, Gilboe I-M, Harbo H F, Maslinski S, Førre Ø, Thorsby E, Lie B A
Abstract excerpt
OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease reported to be associated with several alleles in the HLA complex. The purpose of this study was to systematically examine the extended HLA complex (xMHC) in order to get an overview of the primary predisposing genetic factors. MATERIALS AND METHODS: One hundred and sixty-four SLE patients and 254 healthy, unrelated controls were genotyped for...
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