Major histocompatibility complex extended haplotypes in systemic lupus erythematosus.

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Article

Major histocompatibility complex extended haplotypes in systemic lupus erythematosus.

Disease markers - 1 Jan 2000

Welch T R, Beischel L S, Balakrishnan K, Quinlan M, West C D

Abstract excerpt

In a study of 32 white patients with systemic lupus erythematosus from 28 families, 60 unique chromosome 6 haplotypes were defined. The MHC extended haplotype HLA-B8, -DR3, SC01, GL02 was strongly disease-associated (0.09 patients, 0.02 controls, RR = 4.5, C.I. = 1.6-12.4, P less than 0.05), whil...

Topics

Adolescent
Adult
Aged
Alleles
Autoimmune Diseases
Child
Chromosomes, Human, Pair 6
Complement C4
Complement C4a
Female
Genetic Markers
Haplotypes
Homozygote
Humans
Lupus Erythematosus, Systemic
Major Histocompatibility Complex
Male
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 3266126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3266126-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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