Article
Major histocompatibility complex extended haplotypes in systemic lupus erythematosus.
Disease markers - 1 Jan 2000
Welch T R, Beischel L S, Balakrishnan K, Quinlan M, West C D
Abstract excerpt
In a study of 32 white patients with systemic lupus erythematosus from 28 families, 60 unique chromosome 6 haplotypes were defined. The MHC extended haplotype HLA-B8, -DR3, SC01, GL02 was strongly disease-associated (0.09 patients, 0.02 controls, RR = 4.5, C.I. = 1.6-12.4, P less than 0.05), while the corresponding haplotype with the GL01 specificity was not increased in frequency (0.05 in both patients and...
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