Article
N-cadherin switching occurs in high Gleason grade prostate cancer.
The Prostate - 1 Feb 2006
Jaggi Meena, Nazemi Tanya, Abrahams Neil A, Baker John J, Galich Anton, Smith Lynette M, Balaji K C
Abstract excerpt
BACKGROUND: The inappropriate expression of non-epithelial N-(neural) cadherin by epithelial cells, called cadherin switching, has been suggested to play a role in prostate cancer (PC) progression. We explored the role of N-cadherin as a biomarker in PC by correlating the expression with clinical parameters. METHODS: Two pathologists blinded to patients' history independently reviewed and scored the intensity and...
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