Article
Pan-cadherin as a high level phenotypic biomarker for prostate cancer.
The Journal of urology - 1 May 2002
Wehbi Nizar K, Dugger Ashley L, Bonner Rebecca B, Pitha Jan V, Hurst Robert E, Hemstreet George P
Abstract excerpt
PURPOSE: High level phenotypic biomarkers such as cadherins are needed to identify individuals at risk for biologically active prostate cancer and determine which individuals with elevated prostate specific antigen or a prostate nodule are candidates for re-biopsy. Cadherins are a high level phenotypic biomarker associated with decreased cell adhesion, which is a cardinal event in carcinogenesis. Recently we...
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