Article
Complex cadherin expression in human prostate cancer cells.
International journal of cancer - 1 Feb 2000
Bussemakers M J, Van Bokhoven A, Tomita K, Jansen C F, Schalken J A
Abstract excerpt
Changes in cell-cell interactions are critical in the process of cancer progression. Likewise, it has been shown that loss of expression of the cell adhesion molecule E-cadherin is associated with grade, stage, and prognosis in many carcinomas, including prostate cancer. Impaired E-cadherin-mediated interactions result in an invasive phenotype; however, the mere loss of cell-cell contact and communication is not...
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