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Article

Cadherin Switching and Bladder Cancer

18 Jun 2010

Abstract excerpt

PURPOSE: Progression to or presentation with muscle invasive disease represents the critical clinical step in bladder cancer, necessitating more aggressive therapy and carrying a significantly worse survival rate. Bladder tumors typically show decreased expression of the cell-cell adhesion molecule E-cadherin as grade and stage progress, accompanied by increased expression of N-cadherin or P-cadherin in muscle...

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Identifiers

PMID: 20620393
DOI: 10.1016/j.juro.2010.04.016

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