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Article

Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Sept 2005

Vilella Elisabet, Virgos Carmen, Murphy Michelle, Martorell Lourdes, Valero Joaquín, Simó Josep Maria, Joven Jorge, Fernández-Ballart Joan, Labad Antonio

Abstract excerpt

It has been suggested that total plasma homocysteine (tHcy) concentrations and methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms are risk factors for schizophrenia. We conducted a case-control study to investigate whether tHcy levels and MTHFR C677T and A1298C variants are associated with schizophrenia, giving special consideration to confounding factors. Logistic regression analysis showed that...

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Identifiers

PMID: 16076517
DOI: 10.1016/j.pnpbp.2005.07.001

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Further evidence that hyperhomocysteinemia and methylenetetrahydrofolate reductase C677T and A1289C polymorphisms are not risk factors for schizophrenia.PMID 16076517Read ↗

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