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Article

The BTB-kelch protein KLHL6 is involved in B-lymphocyte antigen receptor signaling and germinal center formation.

Molecular and cellular biology - 1 Oct 2005

Kroll Jens, Shi Xiaozhong, Caprioli Arianna, Liu Hong-Hsing, Waskow Claudia, Lin Keng-Mean, Miyazaki Toru, Rodewald Hans-Reimer, Sato Thomas N

Abstract excerpt

BTB-kelch proteins can elicit diverse biological functions but very little is known about the physiological role of these proteins in vivo. Kelch-like protein 6 (KLHL6) is a BTB-kelch protein with a lymphoid tissue-restricted expression pattern. In the B-lymphocyte lineage, KLHL6 is expressed throughout ontogeny, and KLHL6 expression is strongly upregulated in germinal center (GC) B cells. To analyze the role of...

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Source

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Identifiers

PMID: 16166635
DOI: 10.1128/MCB.25.19.8531-8540.2005
PMCID: PMC1265761

Genes

KLHL6
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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