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Article

A quantitative measurement of the human somatic mutation rate.

Cancer research - 15 Sept 2005

Araten David J, Golde David W, Zhang Rong H, Thaler Howard T, Gargiulo Lucia, Notaro Rosario, Luzzatto Lucio

Abstract excerpt

The mutation rate (mu) is a key biological feature of somatic cells that determines risk for malignant transformation, and it has been exceedingly difficult to measure in human cells. For this purpose, a potential sentinel is the X-linked PIG-A gene, because its inactivation causes lack of glycos...

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PMID: 16166284
DOI: 10.1158/0008-5472.CAN-04-1198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16166284-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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