Article
Lack of Association between IL-10 Gene Promoter Polymorphisms and Susceptible to Tuberculosis in Thai Patients.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Nov 2015
Kulpraneet Manaphol, Limtrakul Anirut, Srisurapanon Surangrat, Tangteerawatana Piyatida
Abstract excerpt
BACKGROUND: Cytokines play a major role in defense against Mycobacterium tuberculosis infection. Polymorphisms in the genes encoding various cytokines have been associated with tuberculosis susceptibility. Polymorphisms of the regulatoy cytokine gene, the interleukin (IL)-10 is associated with the risk of tuberculosis (TB) in different populations. However IL-10 gene polymorphism and susceptibility to TB in Thai...
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