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Article

Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines.

Analytical chemistry - 15 Sept 2005

Ohkura Masamichi, Matsuzaki Masanori, Kasai Haruo, Imoto Keiji, Nakai Junichi

Abstract excerpt

G-CaMP is a Ca2+ probe based on a single green fluorescent protein (GFP). G-CaMP shows a large fluorescence increase upon Ca2+ binding, but its fluorescence is dim and pH sensitive, similar to other single GFP-based probes. Here we report an improved G-CaMP, named G-CaMP1.6, which enables easier...

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PMID: 16159115
DOI: 10.1021/ac0506837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16159115-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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